Basic Information
ID: ALA3095477
Type: Binding
Description: Antagonist activity at human alpha4beta2 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced effect at 1 uM incubated for 8 secs followed by compound washout measured after 241 secs by two-electrode voltage clamp technique
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3095477
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 307.40 | 2.43 | 2.43 |
| 307.40 | 2.43 | 2.43 |
| 296.37 | 1.55 | 1.55 |
| 322.43 | 0.70 | 0.70 |
| 270.38 | 1.86 | 1.86 |
| 314.39 | 1.12 | 1.12 |
| 318.80 | 1.77 | 1.77 |
| 298.34 | 0.83 | 0.83 |