Basic Information
ID: ALA3096357
Type: Binding
Description: Inhibition of MEK1 (unknown origin) assessed as phosphorylation of Erk2 preincubated for 30 mins followed by FAM-Erktide addition measured after 60 mins by IMAP fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3096357
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 479.94 | 3.28 | 3.28 |
| 475.52 | 3.96 | 3.96 |
| 466.52 | 3.46 | 3.46 |
| 571.39 | 3.23 | 3.23 |
| 459.52 | 2.94 | 2.94 |
| 469.52 | 2.61 | 2.61 |
| 470.51 | 2.50 | 2.50 |
| 431.47 | 2.37 | 2.37 |
| 449.46 | 2.51 | 2.51 |
| 449.46 | 2.51 | 2.51 |
| 449.46 | 2.51 | 2.51 |
| 449.46 | 2.51 | 2.51 |
| 449.46 | 2.51 | 2.51 |
| 449.46 | 2.53 | 2.53 |
| 445.50 | 2.63 | 2.63 |
| 463.49 | 2.77 | 2.77 |
| 463.49 | 2.77 | 2.77 |
| 463.49 | 2.77 | 2.77 |
| 463.49 | 2.79 | 2.79 |
| 452.49 | 3.15 | 3.15 |
| 470.48 | 3.29 | 3.29 |
| 457.53 | 3.82 | 3.82 |