Basic Information
ID: ALA3096513
Type: Binding
Description: Inhibition of human cathepsin-K using Z-Leu-Arg-AMC as substrate up to 20 mins by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Cathepsin K(ALA268)
Document: ALA3091448
Inhibition of human cathepsin-K using Z-Leu-Arg-AMC as substrate up to 20 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3096513
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 459.57 | 1.66 | 1.66 |
| 457.55 | 1.42 | 1.42 |
| 443.53 | 0.89 | 0.89 |
| 429.54 | 2.04 | 2.04 |
| 443.57 | 2.29 | 2.29 |
| 444.56 | 0.80 | 0.80 |
| 430.53 | 0.46 | 0.46 |
| 445.54 | 1.01 | 1.01 |
| 479.58 | 0.28 | 0.28 |
| 455.51 | 2.81 | 2.81 |
| 415.52 | 1.65 | 1.65 |
| 401.49 | 1.26 | 1.26 |
| 417.49 | 0.23 | 0.23 |
| 389.48 | 1.12 | 1.12 |
| 387.38 | 1.38 | 1.38 |
| 423.49 | 1.92 | 1.92 |
| 457.94 | 2.57 | 2.57 |
| 463.99 | 2.84 | 2.84 |
| 395.87 | 1.28 | 1.28 |
| 447.54 | 3.77 | 3.77 |
| 301.29 | 0.15 | 0.15 |
| 383.47 | -0.30 | -0.30 |
| 405.48 | 0.35 | 0.35 |
| 439.92 | 1.01 | 1.01 |
| 473.47 | 1.37 | 1.37 |
| 406.46 | -0.58 | -0.58 |
| 440.91 | 0.08 | 0.08 |
| 474.46 | 0.44 | 0.44 |
| 433.53 | 1.13 | 1.13 |
| 431.51 | 0.89 | 0.89 |
| 445.54 | 1.28 | 1.28 |