Basic Information
ID: ALA3096838
Type: Binding
Description: Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced accumulation of ethidium+ at 10 uM after 120 mins by fluorescence assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3096838
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.27 | 2.08 | 2.08 |
| 301.30 | 2.28 | 2.28 |
| 299.28 | 2.66 | 2.66 |
| 331.32 | 2.29 | 2.29 |
| 331.32 | 2.29 | 2.29 |
| 331.32 | 2.29 | 2.29 |
| 345.31 | 1.98 | 1.98 |
| 285.30 | 2.59 | 2.59 |
| 299.33 | 2.78 | 2.78 |
| 297.31 | 3.17 | 3.17 |
| 329.35 | 2.79 | 2.79 |
| 329.35 | 2.79 | 2.79 |
| 329.35 | 2.79 | 2.79 |
| 337.33 | 3.24 | 3.24 |
| 377.40 | 3.87 | 3.87 |
| 379.37 | 3.88 | 3.88 |
| 393.39 | 4.07 | 4.07 |
| 365.34 | 3.95 | 3.95 |
| 379.37 | 3.88 | 3.88 |
| 379.37 | 3.88 | 3.88 |
| 317.30 | 2.21 | 2.21 |
| 316.27 | 1.74 | 1.74 |
| 300.27 | 2.04 | 2.04 |
| 408.37 | 3.54 | 3.54 |
| 347.37 | 3.75 | 3.75 |
| 349.39 | 3.67 | 3.67 |
| 389.41 | 4.39 | 4.39 |
| 391.42 | 4.31 | 4.31 |
| 405.41 | 4.27 | 4.27 |
| 407.42 | 4.19 | 4.19 |
| 321.33 | 3.00 | 3.00 |
| 363.37 | 3.64 | 3.64 |