Basic Information
ID: ALA3097490
Type: Binding
Description: Displacement of [3H2]-25-hydroxycholesterol from N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system after 3 hrs by scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3097490
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.34 | 4.76 | 4.76 |
| 399.31 | 3.80 | 3.80 |
| 425.35 | 3.75 | 3.75 |
| 345.34 | 2.94 | 2.94 |
| 427.37 | 4.21 | 4.21 |
| 506.35 | 4.63 | 4.63 |
| 506.35 | 4.63 | 4.63 |
| 506.35 | 4.63 | 4.63 |
| 495.36 | 5.06 | 5.06 |
| 499.33 | 4.90 | 4.90 |
| 482.32 | 4.15 | 4.15 |
| 445.30 | 3.86 | 3.86 |
| 495.36 | 4.90 | 4.90 |
| 443.37 | 3.19 | 3.19 |
| 457.39 | 3.84 | 3.84 |
| 505.46 | 3.24 | 3.24 |
| 484.42 | 3.33 | 3.33 |
| 471.38 | 3.67 | 3.67 |
| 495.36 | 5.15 | 5.15 |
| 489.44 | 5.39 | 5.39 |
| 495.36 | 5.41 | 5.41 |
| 359.33 | 3.14 | 3.14 |
| 358.34 | 2.54 | 2.54 |
| 394.40 | 2.09 | 2.09 |
| 427.37 | 4.21 | 4.21 |
| 445.28 | 5.21 | 5.21 |
| 363.26 | 4.25 | 4.25 |
| 431.25 | 5.27 | 5.27 |
| 477.41 | 3.52 | 3.52 |