Basic Information
ID: ALA3097607
Type: Binding
Description: Inhibition of mPGES-1 in Swiss mouse NIH/3T3 cells using PGH2 as substrate assessed as inhibition of IL-1beta/TNFalpha-stimulated PGE2 production at 5 uM preincubated for 30 mins followed by substrate addition measured after 1 min by LC-MS/MS analysis
Organism: Mus musculus
Strain: Swiss
Cell type: NIH/3T3
Activity Charts
Bioactivity
Activity Types for Assay ALA3097607
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.53 | 4.16 | 4.16 |
| 458.54 | 5.52 | 5.52 |
| 459.52 | 5.57 | 5.57 |
| 473.55 | 5.57 | 5.57 |
| 463.60 | 5.82 | 5.82 |
| 411.48 | 3.78 | 3.78 |