Basic Information
ID: ALA3101168
Type: Binding
Description: Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIA
Organism: Homo sapiens
Cell type: NCI-H295R
Activity Charts
Bioactivity
Activity Types for Assay ALA3101168
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.28 | 2.68 | 2.68 |
| 306.38 | 5.01 | 5.01 |
| 288.39 | 4.87 | 4.87 |
| 255.30 | 3.21 | 3.21 |
| 271.75 | 3.72 | 3.72 |
| 267.33 | 3.08 | 3.08 |
| 301.73 | 2.27 | 2.27 |
| 297.31 | 1.63 | 1.63 |
| 285.28 | 1.76 | 1.76 |
| 395.82 | 3.98 | 3.98 |
| 404.45 | 3.25 | 3.25 |
| 260.34 | 4.09 | 4.09 |
| 278.33 | 4.22 | 4.22 |
| 243.70 | 2.94 | 2.94 |
| 239.28 | 2.30 | 2.30 |
| 227.24 | 2.43 | 2.43 |
| 223.28 | 2.60 | 2.60 |
| 288.15 | 3.05 | 3.05 |
| 299.38 | 4.35 | 4.35 |
| 274.37 | 4.48 | 4.48 |
| 241.27 | 2.82 | 2.82 |
| 257.72 | 3.33 | 3.33 |
| 237.31 | 2.99 | 2.99 |
| 253.31 | 2.69 | 2.69 |
| 331.39 | 4.88 | 4.88 |