Basic Information
ID: ALA3102127
Type: Functional
Description: Antagonist activity at CRTh2 (unknown origin) expressed in CHO.K1 cells assessed as inhibition of PGD2-induced [35S]-GTPgammaS binding after 2 hrs by liquid scintillation counting
Organism: Homo sapiens
Cell type: CHO.K1
Activity Charts
Bioactivity
Activity Types for Assay ALA3102127
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.50 | 3.16 | 3.16 |
| 447.52 | 3.76 | 3.76 |
| 515.42 | 5.67 | 5.67 |
| 517.61 | 4.07 | 4.07 |
| 483.55 | 2.17 | 2.17 |
| 490.54 | 4.06 | 4.06 |
| 504.56 | 4.15 | 4.15 |
| 447.52 | 3.76 | 3.76 |
| 464.52 | 4.51 | 4.51 |
| 476.55 | 4.38 | 4.38 |
| 460.56 | 4.68 | 4.68 |
| 474.58 | 4.98 | 4.98 |
| 464.52 | 4.51 | 4.51 |
| 480.97 | 5.02 | 5.02 |
| 514.53 | 5.39 | 5.39 |
| 444.56 | 5.69 | 5.69 |
| 476.55 | 4.38 | 4.38 |
| 517.61 | 4.07 | 4.07 |
| 442.58 | 6.30 | 6.30 |
| 458.58 | 5.32 | 5.32 |
| 474.58 | 4.98 | 4.98 |
| 464.52 | 4.51 | 4.51 |
| 480.97 | 5.02 | 5.02 |
| 476.55 | 4.38 | 4.38 |
| 530.52 | 5.27 | 5.27 |
| 489.60 | 4.43 | 4.43 |
| 524.62 | 3.77 | 3.77 |
| 460.56 | 4.51 | 4.51 |
| 497.58 | 4.91 | 4.91 |
| 432.52 | 6.35 | 6.35 |
| 384.46 | 3.01 | 3.01 |
| 386.43 | 1.99 | 1.99 |
| 400.46 | 2.71 | 2.71 |
| 514.53 | 5.39 | 5.39 |
| 464.52 | 4.51 | 4.51 |
| 514.53 | 5.39 | 5.39 |
| 476.55 | 4.38 | 4.38 |
| 446.53 | 4.37 | 4.37 |