Basic Information
ID: ALA3105976
Type: Binding
Description: Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein coupled KISGRLSPIMTEQ as substrate after 30 mins by HPLC analysis in presence of 1 mM ATP
Format: BAO_0000019
Organism: Rattus norvegicus
Target: Dual specificity tyrosine-phosphorylation-regulated kinase 1A(ALA5508)
Document: ALA3102826
Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein coupled KISGRLSPIMTEQ as substrate after 30 mins by HPLC analysis in presence of 1 mM ATP: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3105976
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 302.33 | 4.31 | 4.31 |
| 318.33 | 4.01 | 4.01 |
| 318.33 | 4.01 | 4.01 |
| 334.33 | 3.72 | 3.72 |
| 334.33 | 3.72 | 3.72 |
| 334.33 | 3.72 | 3.72 |
| 302.33 | 4.31 | 4.31 |