Basic Information
ID: ALA3105977
Type: Binding
Description: Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein coupled KISGRLSPIMTEQ as substrate after 30 mins by HPLC analysis in presence of 50 uM ATP
Organism: Rattus norvegicus
Activity Charts
Bioactivity
Activity Types for Assay ALA3105977
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.34 | 4.90 | 4.90 |
| 300.36 | 4.91 | 4.91 |
| 286.33 | 4.60 | 4.60 |
| 300.36 | 4.91 | 4.91 |
| 286.33 | 4.60 | 4.60 |
| 300.36 | 4.91 | 4.91 |
| 286.33 | 4.60 | 4.60 |
| 330.39 | 4.91 | 4.91 |
| 330.39 | 4.91 | 4.91 |
| 302.33 | 4.31 | 4.31 |
| 330.39 | 4.91 | 4.91 |
| 360.41 | 4.92 | 4.92 |
| 360.41 | 4.92 | 4.92 |
| 390.44 | 4.93 | 4.93 |
| 390.44 | 4.93 | 4.93 |
| 390.44 | 4.93 | 4.93 |
| 330.39 | 4.91 | 4.91 |
| 302.33 | 4.31 | 4.31 |
| 318.33 | 4.01 | 4.01 |
| 318.33 | 4.01 | 4.01 |
| 334.33 | 3.72 | 3.72 |
| 334.33 | 3.72 | 3.72 |
| 334.33 | 3.72 | 3.72 |
| 302.33 | 4.31 | 4.31 |
| 302.33 | 4.31 | 4.31 |