Basic Information
ID: ALA3106505
Type: Binding
Description: Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubated for 30 mins followed by ATP addition by Fluo-4 AM dye-based fluorescence assay
Organism: Homo sapiens
Cell type: 1321-N1
Activity Charts
Bioactivity
Activity Types for Assay ALA3106505
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.37 | 3.33 | 3.33 |
| 236.27 | 3.39 | 3.39 |
| 238.29 | 3.00 | 3.00 |
| 254.29 | 2.49 | 2.49 |
| 252.27 | 2.64 | 2.64 |
| 296.33 | 3.06 | 3.06 |
| 252.27 | 3.03 | 3.03 |
| 282.34 | 3.54 | 3.54 |
| 292.38 | 4.77 | 4.77 |
| 250.30 | 3.65 | 3.65 |
| 251.29 | 4.07 | 4.07 |
| 321.42 | 3.97 | 3.97 |
| 254.26 | 3.53 | 3.53 |
| 317.34 | 5.27 | 5.27 |
| 265.32 | 2.93 | 2.93 |
| 251.29 | 2.67 | 2.67 |
| 266.30 | 3.36 | 3.36 |
| 318.42 | 5.35 | 5.35 |
| 340.43 | 5.26 | 5.26 |
| 304.39 | 4.91 | 4.91 |
| 290.37 | 4.52 | 4.52 |
| 264.33 | 3.99 | 3.99 |
| 292.38 | 4.82 | 4.82 |
| 320.44 | 5.55 | 5.55 |
| 321.42 | 3.92 | 3.92 |
| 292.38 | 4.82 | 4.82 |
| 333.44 | 4.11 | 4.11 |
| 324.38 | 2.72 | 2.72 |
| 320.39 | 3.89 | 3.89 |
| 334.42 | 4.32 | 4.32 |
| 333.44 | 4.29 | 4.29 |
| 312.37 | 5.54 | 5.54 |
| 313.36 | 4.94 | 4.94 |
| 320.44 | 5.55 | 5.55 |
| 320.44 | 5.17 | 5.17 |
| 419.57 | 6.03 | 6.03 |
| 250.30 | 3.70 | 3.70 |
| 254.26 | 3.53 | 3.53 |
| 304.27 | 4.41 | 4.41 |
| 266.30 | 3.40 | 3.40 |
| 286.33 | 4.54 | 4.54 |
| 279.34 | 3.45 | 3.45 |
| 293.37 | 4.17 | 4.17 |
| 252.27 | 3.09 | 3.09 |
| 252.27 | 3.09 | 3.09 |
| 235.29 | 3.86 | 3.86 |
| 297.36 | 5.15 | 5.15 |
| 283.37 | 5.51 | 5.51 |
| 293.37 | 5.10 | 5.10 |
| 327.38 | 5.65 | 5.65 |
| 326.40 | 5.22 | 5.22 |
| 306.37 | 3.76 | 3.76 |
| 278.36 | 4.43 | 4.43 |
| 370.45 | 5.27 | 5.27 |