Assay Report Card

Basic Information

ID: ALA3106781

Type: Binding

Description: Inhibition of perforin-mediated lysis of human [51Cr]-labeled K562 cells assessed as release of [51Cr] at 5 uM preincubated for 20 mins with human KHYG-1 cells followed by addition of human [51Cr]-labeled K562 cells measured after 4 hrs by gamma counting analysis in absence of mouse serum

Organism: Homo sapiens

Cell type: K562

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
355.442.052.05