Basic Information
ID: ALA3106783
Type: Binding
Description: Inhibition of perforin-mediated lysis of human [51Cr]-labeled K562 cells assessed as release of [51Cr] at 20 uM preincubated for 20 mins with human KHYG-1 cells followed by addition of human [51Cr]-labeled K562 cells measured after 4 hrs by gamma counting analysis in absence of mouse serum
Organism: Homo sapiens
Cell type: K562
Activity Charts
Bioactivity
Activity Types for Assay ALA3106783
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.47 | 2.91 | 2.91 |
| 355.44 | 2.05 | 2.05 |
| 355.44 | 2.05 | 2.05 |
| 325.35 | 1.84 | 1.84 |
| 336.38 | 1.34 | 1.34 |
| 341.42 | 2.00 | 2.00 |
| 355.44 | 2.35 | 2.35 |
| 385.47 | 1.71 | 1.71 |
| 399.50 | 2.10 | 2.10 |
| 413.48 | 2.87 | 2.87 |