Basic Information
ID: ALA3106983
Type: Binding
Description: Inhibition of human recombinant GST-tagged PFKFB3 expressed in Escherichia coli BL21(DE3) using fructose 6-phosphate as substrate preincubated for 30 mins before substrate addition measured after 60 mins by kinase-glo assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3106983
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 336.19 | 1.83 | 1.83 |
| 408.42 | 0.83 | 0.83 |
| 399.21 | 1.96 | 1.96 |
| 458.19 | 2.99 | 2.99 |
| 408.64 | 2.74 | 2.74 |
| 376.17 | 0.88 | 0.88 |
| 388.23 | 2.15 | 2.15 |
| 309.33 | 1.38 | 1.38 |
| 514.12 | 2.75 | 2.75 |
| 402.25 | 2.34 | 2.34 |
| 416.28 | 2.73 | 2.73 |
| 474.36 | 2.12 | 2.12 |
| 260.30 | 3.53 | 3.53 |
| 343.36 | 3.04 | 3.04 |
| 374.20 | 2.09 | 2.09 |
| 407.27 | 3.43 | 3.43 |
| 348.20 | 1.83 | 1.83 |
| 323.15 | 0.89 | 0.89 |
| 350.22 | 2.59 | 2.59 |
| 329.75 | 1.98 | 1.98 |
| 421.20 | 1.93 | 1.93 |
| 337.38 | 2.45 | 2.45 |
| 339.36 | 1.72 | 1.72 |