ID: ALA3107136
Type: Binding
Description: Inhibition of human HPGD in human ME180 cells assessed as downregulation of TNFalpha-induced NF-kappaB expression at 647 pM to 38.2 uM incubated for 15 mins prior to TNFalpha addition measured after 4 to 24 hrs by beta-lactamase reporter gene assay
Organism: Homo sapiens
Cell type: ME-180
Bioactivity
Activity Types for Assay ALA3107136
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
352.47 | 3.25 | 3.25 |
401.85 | 3.30 | 3.30 |
144.13 | -0.11 | -0.11 |
340.86 | 4.73 | 4.73 |
339.83 | 4.31 | 4.31 |
361.49 | 4.95 | 4.95 |
318.46 | 5.09 | 5.09 |