Basic Information
ID: ALA3107244
Type: Functional
Description: Induction of proimflammatory activity in human primary epidermal keratinocytes assessed as TNFalpha release after 6 hrs relative to ingenol 3-angelate
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Keratinocyte
Target: Keratinocyte(ALA613995)
Document: ALA3102768
Induction of proimflammatory activity in human primary epidermal keratinocytes assessed as TNFalpha release after 6 hrs relative to ingenol 3-angelate: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3107244
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.55 | 2.68 | 2.68 |
| 499.58 | 2.86 | 2.86 |
| 571.71 | 4.60 | 4.60 |
| 587.71 | 4.30 | 4.30 |
| 523.63 | 2.95 | 2.95 |
| 502.61 | 3.83 | 3.83 |
| 531.44 | 3.44 | 3.44 |
| 466.57 | 2.99 | 2.99 |
| 494.63 | 3.80 | 3.80 |
| 482.57 | 2.69 | 2.69 |
| 510.63 | 3.47 | 3.47 |
| 528.65 | 4.35 | 4.35 |
| 544.64 | 4.47 | 4.47 |
| 543.66 | 4.42 | 4.42 |
| 467.56 | 2.26 | 2.26 |
| 481.59 | 2.72 | 2.72 |
| 557.69 | 4.29 | 4.29 |
| 635.89 | 7.01 | 7.01 |
| 691.99 | 8.57 | 8.57 |
| 480.60 | 3.30 | 3.30 |
| 512.60 | 2.70 | 2.70 |
| 521.44 | 3.99 | 3.99 |
| 501.02 | 3.64 | 3.64 |
| 481.59 | 2.57 | 2.57 |
| 497.59 | 2.27 | 2.27 |
| 502.01 | 2.92 | 2.92 |
| 485.55 | 2.40 | 2.40 |
| 482.57 | 2.69 | 2.69 |
| 495.62 | 3.03 | 3.03 |
| 516.03 | 3.38 | 3.38 |