Assay Report Card

Basic Information

ID: ALA3107515

Type: Binding

Description: Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli BL21(DE3) assessed as reduction of oxidized trypanothione at 100 uM preincubated for 30 mins measured for 30 mins by spectrophotometric analysis relative to DMSO-treated control

Organism: Trypanosoma cruzi

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
274.364.914.91
260.344.524.52
360.505.045.04
346.474.654.65
302.425.525.52
276.343.703.70
262.313.313.31
288.395.135.13
350.334.334.33
362.435.615.61
376.466.006.00
362.435.615.61
376.466.006.00
238.293.173.17
252.323.563.56
510.602.872.87
574.697.137.13
370.426.146.14