Basic Information
ID: ALA3107515
Type: Binding
Description: Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli BL21(DE3) assessed as reduction of oxidized trypanothione at 100 uM preincubated for 30 mins measured for 30 mins by spectrophotometric analysis relative to DMSO-treated control
Format: BAO_0000019
Organism: Trypanosoma cruzi
Target: Trypanothione reductase(ALA5131)
Document: ALA3102757
Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli BL21(DE3) assessed as reduction of oxidized trypanothione at 100 uM preincubated for 30 mins measured for 30 mins by spectrophotometric analysis relative to DMSO-treated control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3107515
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 274.36 | 4.91 | 4.91 |
| 260.34 | 4.52 | 4.52 |
| 360.50 | 5.04 | 5.04 |
| 346.47 | 4.65 | 4.65 |
| 302.42 | 5.52 | 5.52 |
| 276.34 | 3.70 | 3.70 |
| 262.31 | 3.31 | 3.31 |
| 288.39 | 5.13 | 5.13 |
| 350.33 | 4.33 | 4.33 |
| 362.43 | 5.61 | 5.61 |
| 376.46 | 6.00 | 6.00 |
| 362.43 | 5.61 | 5.61 |
| 376.46 | 6.00 | 6.00 |
| 238.29 | 3.17 | 3.17 |
| 252.32 | 3.56 | 3.56 |
| 510.60 | 2.87 | 2.87 |
| 574.69 | 7.13 | 7.13 |
| 370.42 | 6.14 | 6.14 |