Basic Information
ID: ALA3107813
Type: Functional
Description: Negative allosteric modulation of rat muscarinic acetylcholine receptor M5 expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization incubated for 150 secs prior to acetylcholine induction by Fluo-4 AM staining-based fluorescence assay
Organism: Rattus norvegicus
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3107813
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.40 | 3.64 | 3.64 |
| 390.39 | 3.78 | 3.78 |
| 424.83 | 4.43 | 4.43 |
| 424.83 | 4.43 | 4.43 |