Basic Information
ID: ALA3108122
Type: Binding
Description: Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current preincubated for 15 mins followed by nicotine-treatment by fluorometric analysis relative to NS9283
Organism: Homo sapiens
Cell type: HEK-tsA201
Activity Charts
Bioactivity
Activity Types for Assay ALA3108122
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.25 | 1.60 | 1.60 |
| 224.23 | 1.12 | 1.12 |
| 259.22 | 3.08 | 3.08 |
| 268.23 | 2.71 | 2.71 |
| 224.22 | 2.19 | 2.19 |
| 248.25 | 1.60 | 1.60 |
| 268.23 | 2.71 | 2.71 |