Basic Information
ID: ALA3108124
Type: Binding
Description: Positive allosteric modulation of human alpha4beta2alpha5 nACHR expressed in HEK-tsA201 cells assessed as potentiation of nicotine-induced current at 1 uM preincubated for 15 mins followed by nicotine-treatment by fluorometric analysis
Organism: Homo sapiens
Cell type: HEK-tsA201
Activity Charts
Bioactivity
Activity Types for Assay ALA3108124
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.25 | 2.67 | 2.67 |
| 248.25 | 1.60 | 1.60 |
| 257.68 | 3.45 | 3.45 |
| 266.26 | 0.82 | 0.82 |
| 248.25 | 1.60 | 1.60 |
| 262.28 | 1.90 | 1.90 |
| 224.23 | 1.12 | 1.12 |
| 257.68 | 2.38 | 2.38 |
| 302.13 | 2.49 | 2.49 |
| 248.25 | 2.67 | 2.67 |
| 247.26 | 3.28 | 3.28 |
| 248.25 | 2.67 | 2.67 |
| 376.29 | 2.10 | 2.10 |
| 223.24 | 2.80 | 2.80 |
| 257.68 | 3.45 | 3.45 |
| 241.22 | 2.94 | 2.94 |
| 259.22 | 3.08 | 3.08 |
| 259.22 | 3.08 | 3.08 |
| 268.23 | 2.71 | 2.71 |
| 268.23 | 2.71 | 2.71 |
| 307.23 | 3.70 | 3.70 |
| 253.26 | 2.81 | 2.81 |
| 224.22 | 2.19 | 2.19 |
| 246.27 | 2.81 | 2.81 |
| 246.27 | 2.81 | 2.81 |
| 246.27 | 2.81 | 2.81 |
| 246.27 | 2.81 | 2.81 |
| 246.27 | 2.81 | 2.81 |
| 247.26 | 2.20 | 2.20 |
| 247.26 | 2.20 | 2.20 |
| 247.26 | 2.41 | 2.41 |
| 247.26 | 2.20 | 2.20 |
| 247.26 | 2.20 | 2.20 |
| 248.25 | 1.60 | 1.60 |
| 390.19 | 1.03 | 1.03 |
| 247.26 | 2.20 | 2.20 |
| 248.25 | 1.60 | 1.60 |
| 282.69 | 2.25 | 2.25 |
| 282.69 | 2.25 | 2.25 |
| 282.69 | 2.25 | 2.25 |
| 282.69 | 2.25 | 2.25 |
| 259.22 | 2.00 | 2.00 |
| 283.29 | 1.74 | 1.74 |
| 292.13 | 3.03 | 3.03 |
| 283.29 | 1.74 | 1.74 |
| 268.23 | 2.71 | 2.71 |
| 291.23 | 3.82 | 3.82 |