Assay Report Card

Basic Information

ID: ALA3108254

Type: Functional

Description: Trypanocidal activity against bloodstream form of Trypanosoma brucei rhodesiense STIB900 infected in NMRI mouse assessed as decrease in parasitemia at 5 mg/kg, ip qd administered for 4 days measured once per week until 60 days by microscopic analysis

Organism: Trypanosoma brucei rhodesiense

Strain: STIB900

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
398.35
423.262.482.48
379.251.971.97
449.173.233.23
379.251.971.97
423.262.482.48
408.292.592.59
438.322.592.59
379.251.971.97
449.173.233.23
449.173.233.23
423.262.482.48
438.322.592.59
378.262.582.58
408.292.592.59
379.251.971.97
453.292.492.49
449.173.233.23
380.241.371.37
379.251.971.97
438.322.592.59
408.292.592.59
449.173.233.23
449.173.233.23
449.173.233.23
379.251.971.97