Basic Information
ID: ALA3108296
Type: Binding
Description: Antagonist activity at NMDA receptor GluN2B subunit in FVB mouse CA1 pyramidal neurons assessed as reversible reduction of excitatory post synaptic current amplitude at 50 nM at holding potential of -60 mV measured for 5 mins by patch clamp technique in presence of Mg2+free ACSF relative to control
Organism: Mus musculus
Strain: FVB
Cell type: Pyramidal neuron
Activity Charts
Bioactivity
Activity Types for Assay ALA3108296
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.45 | 3.72 | 3.72 |