Basic Information
ID: ALA3110615
Type: Binding
Description: Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 120 mins by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: CHOK
Activity Charts
Bioactivity
Activity Types for Assay ALA3110615
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 427.47 | 2.22 | 2.22 |
| 397.47 | 1.77 | 1.77 |
| 455.53 | 3.00 | 3.00 |
| 437.54 | 2.86 | 2.86 |
| 423.51 | 2.47 | 2.47 |
| 409.48 | 2.08 | 2.08 |
| 423.51 | 2.39 | 2.39 |
| 411.50 | 2.08 | 2.08 |
| 421.85 | 2.00 | 2.00 |
| 431.46 | 1.74 | 1.74 |
| 415.46 | 1.91 | 1.91 |