Assay Report Card

Basic Information

ID: ALA3110858

Type: Binding

Description: Positive allosteric modulation of wild type rat alpha1beta2gamma2L GABAA receptor expressed in HEK293 cells assessed as longest-lived intracluster open time at 20 uM by by two-electrode voltage clamp technique relative to control

Organism: Rattus norvegicus

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
262.393.183.18
290.453.963.96
320.473.583.58
276.423.573.57
276.423.573.57