Assay Report Card

Basic Information

ID: ALA3111087

Type: Binding

Description: Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at 900 uM at +15 mV by whole-cell patch-clamp electrophysiology

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
427.20-1.75-1.75
347.22-1.86-1.86
466.43-1.58-1.58
639.30-3.17-3.17
381.67-1.21-1.21
619.42-0.59-0.59