Assay Report Card

Basic Information

ID: ALA3111088

Type: Binding

Description: Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at 100 uM at +15 mV by whole-cell patch-clamp electrophysiology

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
466.43-1.58-1.58
499.31-1.12-1.12
493.43-4.41-4.41
429.44-0.91-0.91
417.43-1.05-1.05
445.48-0.27-0.27
556.54-2.06-2.06
510.40-1.24-1.24
571.421.891.89