Basic Information
ID: ALA3111089
Type: Binding
Description: Antagonist activity at human TRPM2 expressed in HEK293 cells assessed as inhibition of ADPR-induced maximum outward potassium current at +15 mV by whole-cell patch-clamp electrophysiology
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3111089
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 466.43 | -1.58 | -1.58 |
| 499.31 | -1.12 | -1.12 |
| 381.67 | -1.21 | -1.21 |
| 510.40 | -1.24 | -1.24 |
| 571.42 | 1.89 | 1.89 |
| 619.42 | -0.59 | -0.59 |
| 574.33 | -2.86 | -2.86 |
| 577.31 | -3.14 | -3.14 |
| 637.23 | -1.92 | -1.92 |
| 559.31 | -2.97 | -2.97 |
| 560.30 | -3.57 | -3.57 |
| 574.33 | -3.70 | -3.70 |
| 677.45 | -1.41 | -1.41 |
| 641.45 | -1.55 | -1.55 |
| 635.42 | -1.62 | -1.62 |
| 638.21 | -2.52 | -2.52 |