Basic Information
ID: ALA3111842
Type: Binding
Description: Inhibition of TNKS in human SW480 cells assessed as degradation of total pool of beta-catenin after 40 to 48 hrs
Organism: Homo sapiens
Cell type: SW480
Activity Charts
Bioactivity
Activity Types for Assay ALA3111842
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.47 | 4.11 | 4.11 |
| 442.48 | 3.76 | 3.76 |
| 448.55 | 3.78 | 3.78 |
| 424.53 | 3.31 | 3.31 |
| 424.53 | 3.31 | 3.31 |
| 457.98 | 4.57 | 4.57 |
| 448.55 | 3.78 | 3.78 |
| 482.99 | 4.44 | 4.44 |
| 482.99 | 4.44 | 4.44 |
| 437.46 | 4.21 | 4.21 |
| 448.52 | 3.18 | 3.18 |
| 448.52 | 3.18 | 3.18 |
| 443.51 | 3.75 | 3.75 |
| 444.50 | 3.14 | 3.14 |
| 448.53 | 2.95 | 2.95 |
| 512.61 | 4.03 | 4.03 |
| 512.61 | 4.17 | 4.17 |
| 461.55 | 3.91 | 3.91 |
| 457.53 | 4.14 | 4.14 |
| 475.57 | 4.30 | 4.30 |
| 489.60 | 4.69 | 4.69 |
| 479.61 | 4.02 | 4.02 |
| 425.51 | 3.14 | 3.14 |
| 441.53 | 4.05 | 4.05 |
| 457.98 | 4.57 | 4.57 |
| 456.50 | 4.06 | 4.06 |
| 456.50 | 4.06 | 4.06 |
| 456.50 | 3.78 | 3.78 |
| 478.53 | 3.30 | 3.30 |
| 423.48 | 4.05 | 4.05 |
| 423.48 | 4.05 | 4.05 |
| 410.43 | 4.30 | 4.30 |
| 435.49 | 4.55 | 4.55 |
| 435.49 | 4.55 | 4.55 |
| 452.54 | 5.28 | 5.28 |
| 437.46 | 4.21 | 4.21 |