Assay Report Card

Basic Information

ID: ALA3112199

Type: Binding

Description: Antagonist activity at TRPM8 isolated from mouse dorsal root ganglion cells expressed in HEK T-REx cells assessed as inhibition of icilin-induced intracellular Ca2+ influx at 3 to 30 uM preincubated for 3 mins followed by icilin challenge measured after 10 mins of post compound washout

Organism: Mus musculus

Tissue: Dorsal root ganglion

Cell type: HEK T-REx

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
368.483.263.26