Assay Report Card

Basic Information

ID: ALA3116563

Type: Binding

Description: Inhibition of HIV-1 integrase expressed in Escherichia coli using [32P]-labeled U5B/U5A DNA as substrate assessed as inhibition of 3'-processing reaction after 2 hrs by PAGE analysis in presence of Mg2+

Organism: Human immunodeficiency virus 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
351.011.541.54
281.140.780.78
316.570.880.88
350.031.501.50
335.022.222.22
494.035.145.14
309.200.500.50
407.041.381.38