Basic Information
ID: ALA3117199
Type: Binding
Description: Inhibition of Clostridium botulinum BoNT/A LC expressed in Escherichia coli assessed as cleavage of SNAPtide preincubated for 5 mins followed by SNAPtide addition measured for 105 mins by fluorescence assay
Organism: Clostridium botulinum
Activity Charts
Bioactivity
Activity Types for Assay ALA3117199
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 305.50 | 3.20 | 3.20 |
| 145.16 | 1.94 | 1.94 |
| 159.19 | 2.25 | 2.25 |
| 228.08 | 3.56 | 3.56 |
| 371.44 | 4.85 | 4.85 |
| 366.42 | 3.57 | 3.57 |
| 349.43 | 3.62 | 3.62 |
| 386.41 | 4.75 | 4.75 |
| 340.81 | 4.21 | 4.21 |
| 214.05 | 3.25 | 3.25 |
| 375.50 | 5.52 | 5.52 |
| 341.41 | 4.85 | 4.85 |
| 354.84 | 4.60 | 4.60 |
| 322.36 | 3.17 | 3.17 |
| 327.39 | 4.54 | 4.54 |
| 369.47 | 5.62 | 5.62 |
| 354.84 | 4.46 | 4.46 |
| 388.85 | 5.11 | 5.11 |
| 341.41 | 4.85 | 4.85 |
| 355.44 | 5.15 | 5.15 |
| 400.44 | 5.06 | 5.06 |
| 400.44 | 5.06 | 5.06 |
| 342.40 | 4.24 | 4.24 |
| 356.43 | 4.55 | 4.55 |
| 386.41 | 4.75 | 4.75 |
| 400.44 | 5.06 | 5.06 |
| 447.54 | 6.42 | 6.42 |
| 461.57 | 6.73 | 6.73 |
| 385.47 | 5.16 | 5.16 |
| 410.30 | 6.15 | 6.15 |
| 424.33 | 6.46 | 6.46 |
| 387.44 | 4.55 | 4.55 |
| 401.47 | 4.86 | 4.86 |
| 345.38 | 4.68 | 4.68 |
| 359.40 | 4.98 | 4.98 |
| 355.44 | 5.15 | 5.15 |
| 306.37 | 3.47 | 3.47 |
| 335.41 | 3.23 | 3.23 |
| 411.51 | 4.45 | 4.45 |
| 384.48 | 4.91 | 4.91 |
| 398.51 | 5.22 | 5.22 |
| 398.51 | 5.22 | 5.22 |
| 400.44 | 5.06 | 5.06 |
| 357.41 | 4.55 | 4.55 |
| 371.44 | 4.85 | 4.85 |
| 361.47 | 5.22 | 5.22 |
| 361.83 | 5.19 | 5.19 |
| 361.83 | 5.19 | 5.19 |
| 399.45 | 4.71 | 4.71 |
| 399.45 | 4.71 | 4.71 |
| 385.42 | 4.32 | 4.32 |
| 385.42 | 4.32 | 4.32 |
| 413.48 | 5.10 | 5.10 |
| 413.48 | 5.10 | 5.10 |
| 371.44 | 4.85 | 4.85 |
| 371.44 | 4.85 | 4.85 |
| 375.86 | 5.50 | 5.50 |
| 375.86 | 5.50 | 5.50 |
| 341.41 | 4.85 | 4.85 |
| 341.41 | 4.85 | 4.85 |
| 251.29 | 2.95 | 2.95 |
| 319.53 | 3.51 | 3.51 |