Basic Information
ID: ALA3118587
Type: Functional
Description: Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 30 mins relative to isopropyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3118587
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 467.33 | 5.16 | 5.16 |
| 505.38 | 6.15 | 6.15 |
| 393.47 | 4.47 | 4.47 |
| 549.05 | 6.47 | 6.47 |
| 517.39 | 5.68 | 5.68 |
| 571.36 | 6.39 | 6.39 |
| 531.42 | 5.93 | 5.93 |
| 585.39 | 6.48 | 6.48 |
| 557.46 | 6.32 | 6.32 |
| 559.48 | 6.67 | 6.67 |
| 543.43 | 6.25 | 6.25 |
| 543.43 | 6.25 | 6.25 |
| 542.44 | 6.85 | 6.85 |
| 558.51 | 7.32 | 7.32 |
| 561.42 | 6.39 | 6.39 |
| 577.88 | 6.90 | 6.90 |
| 561.42 | 6.39 | 6.39 |
| 577.88 | 6.90 | 6.90 |
| 579.85 | 6.35 | 6.35 |
| 595.92 | 7.06 | 7.06 |
| 627.92 | 5.74 | 5.74 |
| 479.34 | 4.72 | 4.72 |
| 493.37 | 5.11 | 5.11 |
| 507.40 | 5.50 | 5.50 |
| 529.41 | 5.86 | 5.86 |
| 545.45 | 6.50 | 6.50 |
| 543.43 | 6.25 | 6.25 |
| 557.46 | 6.64 | 6.64 |
| 508.99 | 5.60 | 5.60 |
| 534.00 | 5.47 | 5.47 |
| 534.00 | 5.47 | 5.47 |
| 526.98 | 5.74 | 5.74 |
| 543.43 | 6.25 | 6.25 |
| 539.01 | 5.60 | 5.60 |
| 587.08 | 5.00 | 5.00 |
| 534.00 | 5.47 | 5.47 |
| 526.98 | 5.74 | 5.74 |
| 539.01 | 5.60 | 5.60 |
| 587.08 | 5.00 | 5.00 |
| 523.01 | 5.90 | 5.90 |
| 544.97 | 5.87 | 5.87 |
| 544.97 | 5.87 | 5.87 |
| 577.88 | 6.90 | 6.90 |
| 526.98 | 5.74 | 5.74 |
| 523.01 | 5.90 | 5.90 |
| 524.99 | 5.30 | 5.30 |
| 539.01 | 5.60 | 5.60 |