Inhibition of HIV-1 integrase expressed in Escherichia coli using [32P]-labeled U5B/U5A DNA as substrate assessed as inhibition of 3'-processing react...

Basic Information

ID: ALA3119254

Type: Binding

Description: Inhibition of HIV-1 integrase expressed in Escherichia coli using [32P]-labeled U5B/U5A DNA as substrate assessed as inhibition of 3'-processing reaction up to 250 uM after 2 hrs by PAGE analysis in presence of Mg2+

Format: BAO_0000019

Organism: Human immunodeficiency virus 1

Target:  Human immunodeficiency virus type 1 integrase(ALA3471)

Document:  ALA3112550

Inhibition of HIV-1 integrase expressed in Escherichia coli using [32P]-labeled U5B/U5A DNA as substrate assessed as inhibition of 3'-processing reaction up to 250 uM after 2 hrs by PAGE analysis in presence of Mg2+: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
282.120.230.23
284.12-1.02-1.02
281.140.200.20
324.211.401.40
296.150.620.62
283.14-1.06-1.06
360.220.640.64
300.12-1.32-1.32
312.18-0.46-0.46