Basic Information
ID: ALA3119481
Type: Binding
Description: Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preincubated for 10 mins followed by ATP addition measured after 2 hrs by fluorescence based assay
Format: BAO_0000019
Organism: Escherichia coli
Target: GroEL/GroES(ALA4106139)
Document: ALA3112458
Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preincubated for 10 mins followed by ATP addition measured after 2 hrs by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3119481
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 231.25 | 2.50 | 2.50 |
| 316.31 | 2.25 | 2.25 |
| 364.36 | 3.26 | 3.26 |
| 374.40 | 4.78 | 4.78 |
| 570.72 | 7.58 | 7.58 |
| 334.34 | 3.90 | 3.90 |
| 240.27 | 2.21 | 2.21 |
| 310.33 | 1.87 | 1.87 |
| 532.65 | 5.45 | 5.45 |
| 678.75 | 10.20 | 10.20 |
| 423.41 | 3.27 | 3.27 |
| 345.40 | 3.21 | 3.21 |
| 362.34 | 4.34 | 4.34 |
| 352.35 | 3.83 | 3.83 |
| 285.25 | 2.90 | 2.90 |
| 370.25 | 4.97 | 4.97 |
| 249.70 | 2.88 | 2.88 |
| 299.36 | 3.55 | 3.55 |
| 355.42 | 2.17 | 2.17 |
| 361.40 | 3.40 | 3.40 |
| 295.30 | 1.89 | 1.89 |
| 345.40 | 3.22 | 3.22 |
| 314.73 | 3.61 | 3.61 |
| 309.34 | 4.35 | 4.35 |
| 201.19 | 0.88 | 0.88 |
| 323.37 | 4.49 | 4.49 |
| 368.35 | 2.16 | 2.16 |
| 414.51 | 3.63 | 3.63 |
| 383.02 | 3.10 | 3.10 |
| 417.38 | 3.35 | 3.35 |
| 321.34 | 2.71 | 2.71 |
| 376.37 | 3.51 | 3.51 |
| 376.21 | 3.68 | 3.68 |
| 480.52 | 4.72 | 4.72 |
| 327.43 | 3.76 | 3.76 |
| 293.32 | 4.50 | 4.50 |