Basic Information
ID: ALA3124001
Type: Binding
Description: Positive allosteric modulation of rat alpha1beta2gamma2S GABAA receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at 100 uM by two-microelectrode voltage clamp electrophysiology relative to control
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Unchecked(ALA612545)
Document: ALA3120055
Positive allosteric modulation of rat alpha1beta2gamma2S GABAA receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at 100 uM by two-microelectrode voltage clamp electrophysiology relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3124001
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 284.27 | 2.73 | 2.73 |
| 256.26 | 2.07 | 2.07 |
| 408.49 | 4.79 | 4.79 |
| 340.38 | 3.28 | 3.28 |
| 322.36 | 4.19 | 4.19 |
| 342.39 | 3.41 | 3.41 |
| 272.30 | 2.54 | 2.54 |
| 340.38 | 3.67 | 3.67 |
| 280.28 | 3.75 | 3.75 |
| 340.38 | 3.92 | 3.92 |
| 426.51 | 3.99 | 3.99 |
| 340.38 | 3.67 | 3.67 |
| 338.36 | 4.09 | 4.09 |
| 270.28 | 2.97 | 2.97 |
| 322.36 | 4.38 | 4.38 |