Basic Information
ID: ALA3124059
Type: Binding
Description: Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition by time-resolved fluorescence assay
Organism: Hepatitis C virus subtype 1b
Activity Charts
Bioactivity
Activity Types for Assay ALA3124059
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 766.92 | 3.30 | 3.30 |
| 975.22 | 6.60 | 6.60 |
| 875.10 | 4.95 | 4.95 |
| 903.16 | 5.69 | 5.69 |
| 929.19 | 6.08 | 6.08 |
| 933.18 | 5.31 | 5.31 |
| 987.15 | 6.20 | 6.20 |
| 981.25 | 4.71 | 4.71 |
| 957.13 | 6.23 | 6.23 |
| 921.15 | 5.64 | 5.64 |
| 876.09 | 5.38 | 5.38 |
| 903.16 | 5.73 | 5.73 |
| 939.14 | 5.98 | 5.98 |
| 907.12 | 5.25 | 5.25 |
| 925.11 | 5.54 | 5.54 |
| 919.15 | 4.92 | 4.92 |
| 932.20 | 4.84 | 4.84 |
| 889.13 | 5.30 | 5.30 |
| 933.18 | 5.31 | 5.31 |
| 903.16 | 5.68 | 5.68 |
| 901.14 | 5.48 | 5.48 |
| 933.18 | 5.31 | 5.31 |
| 903.16 | 5.68 | 5.68 |
| 959.22 | 5.84 | 5.84 |
| 915.17 | 5.83 | 5.83 |