Basic Information
ID: ALA3124268
Type: ADME
Description: Prodrug coversion in human hepatocytes assessed as triphosphate formation assesed per million cells at 10 uM incubated for 1 hr followed by compound washout by liquid chromatography coupled with mass spectrometry
Organism: Homo sapiens
Cell type: Hepatocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA3124268
Cmax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 546.48 | 0.90 | 0.90 |
| 560.50 | 1.29 | 1.29 |
| 574.53 | 1.67 | 1.67 |
| 588.56 | 2.06 | 2.06 |
| 588.56 | 2.06 | 2.06 |
| 588.56 | 2.06 | 2.06 |
| 600.57 | 2.21 | 2.21 |
| 602.59 | 2.31 | 2.31 |
| 616.61 | 2.70 | 2.70 |
| 622.58 | 2.47 | 2.47 |
| 600.53 | 2.86 | 2.86 |
| 644.62 | 2.88 | 2.88 |