Basic Information
ID: ALA3124461
Type: ADME
Description: Growth inhibition of TNF-alpha stimulated human HEK-293/NF-kB-luc cells assessed as cell viability at 30 uM incubated for 30 mins prior to TNF-alpha challenge for 4 hrs by CellTracker Green CMFDA staining
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: HEK293(ALA614818)
Document: ALA3120079
Growth inhibition of TNF-alpha stimulated human HEK-293/NF-kB-luc cells assessed as cell viability at 30 uM incubated for 30 mins prior to TNF-alpha challenge for 4 hrs by CellTracker Green CMFDA staining: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3124461
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 594.83 | 6.50 | 6.50 |
| 192.17 | 1.51 | 1.51 |
| 432.43 | 3.52 | 3.52 |
| 250.26 | 2.45 | 2.45 |
| 236.23 | 2.14 | 2.14 |
| 650.85 | 2.44 | 2.44 |
| 248.32 | 2.76 | 2.76 |
| 348.40 | 0.65 | 0.65 |
| 346.38 | 0.57 | 0.57 |
| 350.41 | 0.44 | 0.44 |
| 318.37 | 1.29 | 1.29 |
| 316.35 | 1.21 | 1.21 |
| 350.41 | 0.44 | 0.44 |
| 366.41 | -0.59 | -0.59 |
| 396.44 | -1.09 | -1.09 |
| 408.40 | -1.83 | -1.83 |
| 266.26 | 2.15 | 2.15 |
| 226.24 | 2.50 | 2.50 |
| 222.20 | 1.52 | 1.52 |
| 398.37 | -0.38 | -0.38 |
| 362.42 | 1.04 | 1.04 |
| 410.42 | -1.75 | -1.75 |
| 316.74 | 2.46 | 2.46 |
| 348.40 | 0.65 | 0.65 |