Inhibition of NF-kappaB activity in TNF-alpha stimulated human HEK-293/NF-kB-luc cells at 30 uM incubated for 30 mins prior to TNF-alpha challenge for...

Basic Information

ID: ALA3124463

Type: Binding

Description: Inhibition of NF-kappaB activity in TNF-alpha stimulated human HEK-293/NF-kB-luc cells at 30 uM incubated for 30 mins prior to TNF-alpha challenge for 4 hrs by luciferase reporter gene assay

Format: BAO_0000019

Organism: Homo sapiens

Target: Unchecked(ALA612545)

Document: ALA3120079

Inhibition of NF-kappaB activity in TNF-alpha stimulated human HEK-293/NF-kB-luc cells at 30 uM incubated for 30 mins prior to TNF-alpha challenge for 4 hrs by luciferase reporter gene assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3124463

Inhibition

Total(17)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
432.43	3.52	3.52
250.26	2.45	2.45
236.23	2.14	2.14
348.40	0.65	0.65
346.38	0.57	0.57
350.41	0.44	0.44
350.41	0.44	0.44
366.41	-0.59	-0.59
396.44	-1.09	-1.09
408.40	-1.83	-1.83
266.26	2.15	2.15
226.24	2.50	2.50
398.37	-0.38	-0.38
362.42	1.04	1.04
410.42	-1.75	-1.75
316.74	2.46	2.46
348.40	0.65	0.65