Assay Report Card

Basic Information

ID: ALA3124627

Type: Binding

Description: Inhibition of TNFalpha-induced NFkappaB activation in human MDA-MB-231 cells assessed as reduction of NFkappaB-DNA binding activity at 50 uM preincubated for 30 mins followed by cytokine challenge measured after 60 mins by electrophoretic mobility shift assay

Organism: Homo sapiens

Cell type: MDA-MB-231

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
602.819.069.06
602.818.918.91
602.819.069.06