Basic Information
ID: ALA3124716
Type: Functional
Description: Negative allosteric modulation of rat mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux after 16 to 24 hrs by FLIPR assay
Organism: Rattus norvegicus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3124716
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 378.39 | 2.17 | 2.17 |
| 340.39 | 1.82 | 1.82 |
| 316.36 | 3.61 | 3.61 |
| 317.35 | 3.00 | 3.00 |
| 317.35 | 3.00 | 3.00 |
| 318.34 | 2.40 | 2.40 |
| 332.37 | 2.71 | 2.71 |
| 332.37 | 2.71 | 2.71 |
| 386.34 | 3.42 | 3.42 |
| 384.35 | 3.00 | 3.00 |
| 366.81 | 3.36 | 3.36 |
| 333.36 | 2.10 | 2.10 |
| 335.37 | 2.05 | 2.05 |
| 346.39 | 3.19 | 3.19 |
| 358.41 | 3.51 | 3.51 |
| 353.43 | 2.78 | 2.78 |
| 325.37 | 2.00 | 2.00 |
| 353.43 | 2.73 | 2.73 |
| 339.40 | 2.42 | 2.42 |
| 351.41 | 2.57 | 2.57 |
| 353.38 | 1.41 | 1.41 |