Basic Information
ID: ALA3128635
Type: Binding
Description: Inhibition of Hepatitis C virus genotype 1a H77 recombinant NS3/4A protease expressed in Escherichia coli BL21 (DE3) cell using Ac-Asp-Glu-Asp(EDANS)-Glu-Glu-Abu[C(O)-O]-Ala-Ser-Lys(DABCYL)-NH2 as substrate by FRET assay
Organism: Hepatitis C virus (isolate H77)
Cell type: BL21-DE3
Activity Charts
Bioactivity
Activity Types for Assay ALA3128635
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 789.95 | 4.87 | 4.87 |
| 825.99 | 5.76 | 5.76 |
| 791.97 | 5.11 | 5.11 |
| 803.98 | 5.26 | 5.26 |
| 818.01 | 5.65 | 5.65 |
| 713.85 | 3.20 | 3.20 |
| 697.86 | 3.50 | 3.50 |
| 713.85 | 3.20 | 3.20 |
| 768.93 | 3.03 | 3.03 |
| 718.27 | 3.85 | 3.85 |
| 697.86 | 3.50 | 3.50 |
| 713.85 | 3.20 | 3.20 |
| 701.82 | 3.33 | 3.33 |
| 768.93 | 3.03 | 3.03 |
| 749.89 | 3.38 | 3.38 |
| 754.91 | 2.89 | 2.89 |
| 718.27 | 3.85 | 3.85 |
| 697.86 | 3.50 | 3.50 |
| 739.94 | 4.49 | 4.49 |
| 708.84 | 3.06 | 3.06 |
| 699.83 | 2.90 | 2.90 |
| 701.82 | 3.33 | 3.33 |
| 727.88 | 3.59 | 3.59 |
| 697.86 | 3.50 | 3.50 |
| 697.86 | 3.50 | 3.50 |
| 743.88 | 3.21 | 3.21 |
| 713.85 | 3.20 | 3.20 |
| 714.84 | 2.60 | 2.60 |
| 789.95 | 4.87 | 4.87 |
| 713.85 | 3.20 | 3.20 |
| 715.87 | 3.42 | 3.42 |
| 727.84 | 2.19 | 2.19 |
| 699.83 | 2.81 | 2.81 |
| 610.71 | 3.68 | 3.68 |
| 684.83 | 5.85 | 5.85 |
| 763.91 | 4.33 | 4.33 |
| 777.94 | 4.72 | 4.72 |
| 832.03 | 6.04 | 6.04 |
| 763.91 | 4.46 | 4.46 |
| 733.84 | 3.45 | 3.45 |
| 689.84 | 3.30 | 3.30 |
| 747.87 | 3.70 | 3.70 |
| 713.85 | 3.20 | 3.20 |
| 633.77 | 2.04 | 2.04 |
| 709.87 | 3.71 | 3.71 |
| 683.83 | 3.19 | 3.19 |
| 683.83 | 3.19 | 3.19 |
| 759.93 | 4.86 | 4.86 |
| 718.27 | 3.85 | 3.85 |