Basic Information
ID: ALA3128665
Type: Functional
Description: Antagonist activity at human CRTH2 receptor expressed in HEK cells assessed as inhibition of forskolin-induced cAMP formation preincubated for 10 mins followed by forskolin challenge measured after 10 to 60 mins by ELISA assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3128665
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.57 | 5.45 | 5.45 |
| 529.57 | 4.94 | 4.94 |
| 529.57 | 4.94 | 4.94 |
| 540.55 | 5.50 | 5.50 |
| 556.62 | 5.97 | 5.97 |
| 513.57 | 5.45 | 5.45 |
| 499.54 | 5.36 | 5.36 |
| 513.57 | 5.75 | 5.75 |
| 527.60 | 6.14 | 6.14 |
| 515.54 | 4.33 | 4.33 |
| 529.57 | 4.99 | 4.99 |
| 561.61 | 6.39 | 6.39 |
| 499.54 | 5.36 | 5.36 |
| 517.53 | 5.50 | 5.50 |
| 535.52 | 5.64 | 5.64 |
| 533.99 | 6.02 | 6.02 |
| 524.55 | 5.23 | 5.23 |