Basic Information
ID: ALA3129194
Type: Binding
Description: Binding affinity to N-terminal GST-His-tagged recombinant human PAK1 kinase domain expressed in Escherichia coli BL21 using KKRNRRLSVA as sustrate preincubated for 10 mins followed by ATP addition measured after 60 mins by FRET-based Z'Lyte assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3129194
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 366.43 | 1.58 | 1.58 |
| 406.49 | 2.50 | 2.50 |
| 490.64 | 4.53 | 4.53 |
| 308.35 | 1.22 | 1.22 |
| 322.37 | 1.47 | 1.47 |
| 324.34 | 0.20 | 0.20 |
| 348.41 | 2.00 | 2.00 |
| 322.33 | 0.21 | 0.21 |
| 350.38 | 0.99 | 0.99 |
| 348.41 | 2.15 | 2.15 |
| 360.42 | 2.00 | 2.00 |
| 375.39 | 1.66 | 1.66 |
| 377.43 | 1.82 | 1.82 |
| 372.39 | 1.15 | 1.15 |
| 337.39 | 1.35 | 1.35 |
| 293.33 | 1.52 | 1.52 |
| 293.33 | 1.52 | 1.52 |