Basic Information
ID: ALA3129312
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes assessed as dextromethorphan O-demethylation
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2D6(ALA289)
Document: ALA3124772
Inhibition of CYP2D6 in human liver microsomes assessed as dextromethorphan O-demethylation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3129312
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.55 | 3.30 | 3.30 |
| 434.57 | 3.60 | 3.60 |
| 448.59 | 3.91 | 3.91 |
| 417.51 | 2.80 | 2.80 |
| 448.59 | 3.79 | 3.79 |