Basic Information
ID: ALA3129373
Type: Functional
Description: Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as increase in intracellular cAMP accumulation at 10'-10 to 10'-5 M after 30 mins by time-resolved fluorescence assay relative to R-(-)isoproterenol
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Beta-3 adrenergic receptor(ALA246)
Document: ALA3124772
Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as increase in intracellular cAMP accumulation at 10'-10 to 10'-5 M after 30 mins by time-resolved fluorescence assay relative to R-(-)isoproterenol: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3129373
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 422.55 | 3.30 | 3.30 |
| 433.58 | 4.21 | 4.21 |
| 434.57 | 3.60 | 3.60 |
| 447.60 | 4.52 | 4.52 |
| 448.59 | 3.91 | 3.91 |
| 461.63 | 4.77 | 4.77 |
| 462.62 | 4.17 | 4.17 |
| 474.63 | 4.48 | 4.48 |
| 527.67 | 6.01 | 6.01 |
| 528.65 | 5.41 | 5.41 |
| 391.48 | 2.31 | 2.31 |
| 405.50 | 2.87 | 2.87 |
| 417.51 | 2.80 | 2.80 |
| 436.58 | 3.86 | 3.86 |
| 436.58 | 3.86 | 3.86 |
| 450.61 | 4.25 | 4.25 |
| 464.64 | 4.64 | 4.64 |
| 464.64 | 4.50 | 4.50 |
| 448.59 | 3.79 | 3.79 |
| 448.59 | 3.79 | 3.79 |
| 462.62 | 4.18 | 4.18 |
| 476.65 | 4.57 | 4.57 |
| 483.04 | 4.44 | 4.44 |
| 466.58 | 3.93 | 3.93 |
| 466.58 | 3.93 | 3.93 |
| 449.58 | 3.19 | 3.19 |