Basic Information
ID: ALA3129465
Type: Functional
Description: Antagonist activity at smoothened (unknown origin) expressed in mouse Shh Light2 cells co-expressing Gli-dependent reporter gene assessed as inhibition of Shh signaling at 2 uM by dual luciferase reporter gene assay
Organism: Homo sapiens
Cell type: Shh Light II
Activity Charts
Bioactivity
Activity Types for Assay ALA3129465
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.38 | 5.30 | 5.30 |
| 522.41 | 5.69 | 5.69 |
| 512.80 | 5.95 | 5.95 |
| 575.24 | 6.19 | 6.19 |
| 531.34 | 5.92 | 5.92 |
| 523.39 | 4.92 | 4.92 |
| 464.33 | 4.30 | 4.30 |
| 498.78 | 4.95 | 4.95 |
| 503.82 | 5.62 | 5.62 |
| 477.37 | 5.21 | 5.21 |
| 477.37 | 5.21 | 5.21 |
| 491.40 | 5.46 | 5.46 |
| 491.40 | 5.52 | 5.52 |
| 491.40 | 5.52 | 5.52 |
| 479.34 | 4.61 | 4.61 |
| 493.37 | 4.91 | 4.91 |
| 507.40 | 5.30 | 5.30 |
| 532.23 | 6.21 | 6.21 |
| 532.23 | 6.21 | 6.21 |
| 464.33 | 4.30 | 4.30 |