Basic Information
ID: ALA3129689
Type: Binding
Description: Inhibition of Escherichia coli RNAP assessed as incorporation of [5,6-3H]UTP at 100 uM preincubated for 10 mins followed by DNA template and ATP, CTP, GTP, UTP, [5,6-3H]UTP addition measured after 10 mins by scintillation counting analysis
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3129689
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 410.88 | 3.32 | 3.32 |
| 394.42 | 2.81 | 2.81 |
| 421.43 | 2.58 | 2.58 |
| 473.32 | 3.57 | 3.57 |
| 452.53 | 4.33 | 4.33 |
| 317.34 | 4.30 | 4.30 |
| 317.34 | 4.30 | 4.30 |