Basic Information
ID: ALA3129690
Type: Binding
Description: Inhibition of Escherichia coli RNAP assessed as incorporation of [5,6-3H]UTP at 50 uM preincubated for 10 mins followed by DNA template and ATP, CTP, GTP, UTP, [5,6-3H]UTP addition measured after 10 mins by scintillation counting analysis
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3129690
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 496.54 | 4.03 | 4.03 |
| 444.43 | 3.69 | 3.69 |
| 455.33 | 3.43 | 3.43 |
| 534.23 | 4.19 | 4.19 |
| 399.47 | 6.03 | 6.03 |