Basic Information
ID: ALA3129691
Type: Binding
Description: Inhibition of Escherichia coli RNAP assessed as incorporation of [5,6-3H]UTP at 200 uM preincubated for 10 mins followed by DNA template and ATP, CTP, GTP, UTP, [5,6-3H]UTP addition measured after 10 mins by scintillation counting analysis
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA3129691
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.33 | 3.43 | 3.43 |
| 390.42 | 1.66 | 1.66 |
| 376.43 | 2.67 | 2.67 |
| 374.42 | 2.42 | 2.42 |
| 340.38 | 3.12 | 3.12 |
| 376.43 | 2.67 | 2.67 |
| 394.42 | 2.81 | 2.81 |
| 392.43 | 2.37 | 2.37 |
| 495.56 | 3.43 | 3.43 |
| 496.54 | 4.03 | 4.03 |
| 320.33 | 1.28 | 1.28 |
| 348.38 | 1.89 | 1.89 |
| 404.49 | 3.45 | 3.45 |
| 388.45 | 2.81 | 2.81 |
| 402.47 | 3.20 | 3.20 |
| 438.51 | 3.85 | 3.85 |
| 390.46 | 2.98 | 2.98 |
| 404.49 | 3.23 | 3.23 |
| 394.42 | 2.81 | 2.81 |
| 421.43 | 2.58 | 2.58 |
| 390.46 | 2.98 | 2.98 |
| 401.44 | 2.54 | 2.54 |
| 455.33 | 3.43 | 3.43 |
| 419.28 | 3.88 | 3.88 |
| 406.46 | 2.68 | 2.68 |
| 410.88 | 3.32 | 3.32 |
| 396.24 | 5.07 | 5.07 |
| 323.37 | 4.37 | 4.37 |
| 323.37 | 4.37 | 4.37 |